Also, we present the experimentally measured volt-watt responsivity (S~) within the frequency range ω ≈ (0.3-6) THz VN HEB detector. The estimated values of noise equivalent power (NEP) for VN HEB and its minimum energy level (δE) reached NEP@1MHz ≈ 6.3 × 10-14 W/√Hz and δE ≈ 8.1 × 10-18 J, respectively.This study aimed to validate the Clinical Treatment Score post-5 years (CTS5)-based risk stratification in a cohort comprising pre- and postmenopausal patients with estrogen receptor (ER)-positive breast cancer. We investigated the clinicopathologic parameters including Ki-67 labelling index (LI) to identify factors affecting late distant recurrence (DR). Women with ER-positive breast cancer who were free of DR for 5 years were identified between January 2004 and December 2009. We investigated the risk of late DR (5-10 years) according to the CTS5 risk group. Cox regression analysis was used to determine the prognostic performance of CTS5 and identify factors associated with late DR. FUT-175 In all, 680 women were included. Of these, 379 (55.7%) were premenopausal and 301 (44.3%) were postmenopausal. At a median follow-up of 118 months, 32 women had late DR. CTS5 was a significant prognostic factor for late DR in both pre- and postmenopausal women. In the low CTS5 group, high Ki-67 LI (> 20%) was a significant risk factor for late DR. CTS5 is a useful tool for assessing the risk of late DR in pre- and postmenopausal women with ER-positive breast cancer. Extended endocrine therapy can be considered in patients with high Ki-67 LI (> 20%) in the low CTS5 group.To research the dynamic response characteristics of coal mass under impact loads, based on LS-DYNA software, rigid body bars are simulated to impact coal mass under different speed conditions, and the dynamic distribution characteristics of the stress, strain and energy of coal mass are analyzed. The results demonstrate that (1) the peaks of the axial and radial stresses and strain on the central axis and the radial line obey the power function distribution; at the same position, the axial and the radial stress peaks are close, and the axial strain peak is from much larger than the radial strain peak to close to. (2) The axial and radial stresses generate tensile stresses in the axial and radial propagation directions, respectively, and the coal mass is prone to damage under tensile stress. (3) When the speed is large, the axial stress-strain curve is similar to that of the dynamic load experiment. The axial stress peak, axial strain peak, critical effective stress, critical time and secant modulus have a linear relationship with the velocity. (4) When the dynamic load is large, most of the energy is in the form of kinetic energy, and the total energy loss also increases.Carbon nanotubes (CNTs) embedded polymers are of increasing interest to scientific and industrial communities for multi-functional applications. In this article, CNTs have been introduced to high-strength epoxy adhesive for enabling in-situ strain sensing in adhesively bonded aluminium-to-aluminium single-lap joints to accurately indicate the onset and propagation of adhesion failure to the evolution of piezo-resistivity in varying mechanical loads. The CNT modified adhesive in bonded joints and the CNT modified adhesive alone have been tested under monothonic and cyclic tensile loads up to ultimate failure. The changes in the piezo-resistivity induced by the CNTs have been monitored in situ with respect to loading. A novel interpretation method has been developed for progressive, instantaneous adhesion failure estimation under cyclic tensile stresses from a resistivity baseline. The method indicates that the in-situ resistivity changes and the rate of the changes with strain, i.e. sensitivity, strongly correlate with the adhesion failure progression, irrespective of the CNT dispersion quality. Moreover, the effect of bond thickness on the evolution of piezo-resistivity and adhesion failure have been studied. It was observed that relatively thin adhesive bonds (0.18 mm thickness), possessing higher CNT contact points than thick bonds (0.43 mm thickness), provide 100 times higher sensitivity to varying cyclic loads.When we see a face, we rapidly form an impression of its attractiveness. Here, we investigated how rapidly representations of facial attractiveness emerge in the human brain. In an EEG experiment, participants viewed 100 face photographs and rated them for their attractiveness. Using time-resolved representational similarity analysis on the EEG data, we reveal representations of facial attractiveness after 150-200 ms of cortical processing. Interestingly, we show that these representations are related to individual participants’ personal attractiveness judgments, suggesting that already early perceptual representations of facial attractiveness convey idiosyncratic attractiveness preferences. Further, we show that these early representations are genuinely related to attractiveness, as they are neither explained by other high-level face attributes, such as face sex or age, nor by features extracted by an artificial deep neural network model of face processing. Together, our results demonstrate early, individually specific, and genuine representations of facial attractiveness, which may underlie fast attractiveness judgments.Facial expression is an integral aspect of non-verbal communication of affective information. Earlier psychological studies have reported that the presentation of prerecorded photographs or videos of emotional facial expressions automatically elicits divergent responses, such as emotions and facial mimicry. However, such highly controlled experimental procedures may lack the vividness of real-life social interactions. This study incorporated a live image relay system that delivered models’ real-time performance of positive (smiling) and negative (frowning) dynamic facial expressions or their prerecorded videos to participants. We measured subjective ratings of valence and arousal and facial electromyography (EMG) activity in the zygomaticus major and corrugator supercilii muscles. Subjective ratings showed that the live facial expressions were rated to elicit higher valence and more arousing than the corresponding videos for positive emotion conditions. Facial EMG data showed that compared with the video, live facial expressions more effectively elicited facial muscular activity congruent with the models’ positive facial expressions.