ry and alternative therapy to reduce pain and fatigue and enhance quality of life in MS patients.

The study indicates that reflexology can be used as a complementary and alternative therapy to reduce pain and fatigue and enhance quality of life in MS patients.

Platelet hyperactivity has a crucial role in initiating vascular thrombosis and subsequent cardiovascular disease (CVD).

This study aimed to assess the effect of anthocyanins (AC) on platelet aggregation and activation and lipid profile.

A total of 26 healthy participants consumed 320 mg of AC/day in the form of Medox® capsules for 28 days.

This study was conducted in the laboratories of the School of Medical Sciences, Griffith University, Gold Coast, Australia.

A total of 26 randomly recruited healthy 25- to 75-year-old participants completed this study.

Fasting blood samples were collected pre- and post-the intervention period to perform platelet activation studies by measuring platelet surface marker expression of CD41a and P-selectin, and platelet-monocyte aggregates in adenosine diphosphate (ADP) stimulated platelets. Platelet aggregation studies were performed by stimulating platelets with various agonists such as ADP, collagen and arachidonic acid. Selleckchem BI-2865 Full blood examination, coagulation and biochemistry profile analyses were also performed pre- and post-intervention. Flow cytometric analysis showed a significant effect of AC on the expression of P-selectin as measured by the platelet surface expression of CD62p.

There was a significant reduction of ADP-stimulated platelet aggregation. Hematologic analysis showed a significant reduction of mean platelet volume, mean cell hemoglobin, and mean cell hemoglobin concentration. Coagulation analysis demonstrated significant attenuation of fibrinogen level in the blood.

This study showed inhibition of platelet activity, platelet aggregation and mean platelet volume (MPV). These results suggest that AC has a positive impact on attenuating platelet activity, which might minimize thrombotic risk.

This study showed inhibition of platelet activity, platelet aggregation and mean platelet volume (MPV). These results suggest that AC has a positive impact on attenuating platelet activity, which might minimize thrombotic risk.

Energy metabolism is the main determinant of obesity etiology. Consumption of some spices, such as red pepper, ginger, and turmeric, can be considered to be an environmental factor affecting energy metabolism.

This review aimed to examine the effects of red pepper, ginger, and turmeric on weight control, weight loss, and energy metabolism.

The research team performed a narrative review by searching the Google scholar, Scopus, PubMed, ResearchGate, Web of Science, and Science Direct databases. The search used the keywords red pepper, ginger, and turmeric in combination with energy metabolism, energy expenditure, energy balance, thermogenesis, anti-obesity, weight management, weight control, weight loss, metabolic rate, and oxygen consumption, without considering any time limitation.

This study has been carried out in Ankara / Turkey.

Red pepper, ginger, and turmeric affect energy metabolism through various mechanisms. Dietary red pepper and its pungent principle capsaicin affects satiety and has a prto conduct further randomized controlled research to reach absolute conclusions and determine by which mechanisms these spices show this effect on energy metabolism.

The World Health Organization (WHO) has defined burnout syndrome (BOS) as resulting from chronic workplace stress that hasn’t been successfully managed. Until now, BOS has been treated using allopathic drugs and psychotherapy because it has been confused with major depressive syndrome.

The aim of the study was to examine the effectiveness of hypnotherapy combined with cognitive-behavioral therapy in changing the personality traits and lifestyles of people in professions vulnerable to stress who have developed BOS.

The research team designed a one-group pre-and posttest study.

The study was conducted in a private-practice office in Targu Mures, Romania.

Participants were 30 patients at the private practice who had been diagnosed with BOS and volunteered to participate in the study.

The study alternated hypnotherapy sessions with psychological-counseling sessions, using a general therapeutic plan for all patients and customizing the plan for each participant.

The study measured participants’ BOS s to BOS.

Diabetic neuropathy, a common debilitating complication of type 2 diabetes, can occur despite adequate treatment. To date, no studies have occurred on the use alternative medicine as an adjunct therapy for treating diabetic neuropathy.

The study assessed the effects of three months of honey supplementation on insulin resistance, lipid profiles, oxidant status, nerve conduction, and QOL in patients with diabetic neuropathy.

The research team designed a single-arm, open-label pilot study.

The study took place at the Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) in Puducherry, India.

The study included 48 patients with diabetic neuropathy at the institute, with a mean age of 58.91 ± 7.976 years.

Participants took honey for three months at a dose of 0.5 gm/Kg of body weight per day.

Participants completed the Neuropathy Total Symptom Score-6 (NTSS-6) questionnaire and the Norfolk QOL Diabetic Neuropathy (Norfolk QOL-DN) questionnaire at baseline and postintervention. Ae pain scores and symptoms from diabetic neuropathy and improved their QOL. However, the nerve conduction study showed that no significant change had occurred in motor velocity.

To investigate the relationship between physical fitness and repeated high-intensity effort (RHIE) ability in elite rugby union players, depending on playing position.

Thirty-nine players underwent a fitness testing battery composed of a body composition assessment, upper-body strength (1-repetition maximum bench press and 1-repetition maximum bench row), lower-body strength (6-repetition maximum back squat), and power (countermovement jump, countermovement jump with arms, and 20-m sprint), as well as aerobic fitness (Bronco test) and RHIE tests over a 1-week period. Pearson linear correlations were used to quantify relationships between fitness tests and the RHIE performance outcomes (total sprint time [TST] and percentage decrement [%D]). Thereafter, a stepwise multiple regression model was used to verify the influence of physical fitness measures on RHIE ability.

TST was strongly to very strongly associated to body fat (BF, r = .82, P < .01), the 20-m sprint (r = .86, P < .01), countermovement jump (r = -.