• Woodard Erichsen posted an update 5 days, 11 hours ago

    Such findings should give biology educators, reformers, and researchers pause, as well as fresh incentive to engage more fully and regularly with administrators about their work.Aim In this study, we aimed to determine the incidence of hair loss in patients who underwent laparoscopic sleeve gastrectomy (LSG), and to observe whether use of Biotin has an impact on hair loss. Methods This study included 156 female patients who underwent LSG for obesity and completed a 1-year follow-up. All patients with vitamin deficiency were screened in the pre- and postoperative period. Hair loss was defined as the subjective perception of the women of losing a higher amount of hair when compared with normal situation. Results Hair loss was observed in 72% of the patients after LSG (n = 112). Seventy-nine percent of the patients reported hair loss between the third and fourth-month interval, and continued for an average of 5.5 ± 2.6 months. Permanent alopecia was not observed in any of the patients. Patients who experienced hair loss and Biotin deficiency after LSG were prescribed 1000 mcg/day of Biotin for 3 months. Of these 22 patients; only 5 (23%) patients reported a remarkable decline in hair loss. İn addition, 29 patients were found to take 1000 mcg/day of Biotin for average 2.5 months after onset of hair loss by their own initiative, despite optimal blood Biotin levels. Eleven (38%) patients reported a remarkable decline in hair loss. The effect of biotin use on hair loss in patients with and without biotin deficiency was compared. There was no significant difference (P = .2). Conclusion Temporary hair loss after LSG is common. It was found that biotin supplementation used to prevent hair loss does provide low efficacy.The ability of the adrenocorticotropic hormone (ACTH) to induce steroidogenesis and upregulate anti-inflammatory processes has long been known. More recently, however, extrasteroidal mechanisms, through which ACTH exerts anti-inflammatory processes, have been described. This has renewed hope that ACTH can combat inflammatory conditions even when resistant to steroids. This review article summarizes the literature on the use of ACTH in ocular disease. Unfortunately, much of the data regarding the clinical utility of ACTH are outdated, with many studies published in the 1950s and 1960s. Many of these older studies are inconsistent or incomplete with their reporting, making it difficult to ascertain the meaning of the outcomes. Phenylbutyrate Despite the limitations, 2 important trends are evident. First, when used to treat an inflammatory disease, ACTH can be effective at decreasing or eliminating ocular inflammation, even in a refractory disease resistant to multiple treatment modalities. Second, adverse effects of ACTH are rare and are most likely to be reported with relatively high doses of ACTH therapy. Taken as a whole, these studies offer initial promising data that ACTH may be a safe and effective alternative in refractory ocular inflammatory disease. However, they highlight an important lack of prospective data to more rigorously understand the true safety and efficacy of this therapy.Background This study is the first to document knowledge-base and knowledge attitudes about cultural competence and religious literacy in hospice and palliative care in Cyprus. Objective The aim of this article is to investigate and document the knowledge-base and attitudes toward advancing knowledge and expertise of hospice and palliative care professionals in Cyprus. Measurements A cross-sectional self-administered online survey, which reached 80 hospice and palliative care professionals employed in the sector, was used. The response rate was 64%, which increases the generalizability of the results. Forty-one surveys were completed fully and included in the study. The study was approved by the Ethics Committee of the Frederick University in Cyprus (EEBK EP 2019.01.28). Results This study shows that self-awareness, reflexivity, and respect toward the other and other people’s culture and religion are associated with the current knowledge-base of the professionals, as well as attitudes toward future learning opportunities, lifelong learning, and initiating learning between professionals and agencies. The results present three themes knowledge development, knowledge empowerment, and knowledge exchange. Conclusions Professionals and organizations need to nurture and promote lifelong learning, supervision, and enable individual practitioners to engage with activities that will enhance their self-awareness, reflexivity, and attitude toward the unique identities of others.Purpose Sarcasm is a specialized speech act in daily vocal communication usually characterized by unique prosodic features, but the role of voice quality in expressing sarcasm has not been explored much. The goal of this study is to explore the voice quality features of Mandarin sarcastic speech in comparison to sincere speech. Method Fifteen male and 15 female native speakers of Mandarin uttered 31 target sentences with both sincere and sarcastic attitudes. Nine voice quality parameters extracted from the acoustic and electroglottographic signals were analyzed using a linear mixed model, and a classification analysis using a random forest algorithm was conducted to identify the relative contribution of these parameters to the differentiation between sincere and sarcastic utterances. Results In comparison to sincere speech, sarcastic speech had a creakier voice, which was characterized by a lower fundamental frequency, a greater degree of vocal fold adduction (i.e., higher contact quotient), lesser noise (i.e., higher harmonics-to-noise ratio), and more multiple pulsing (i.e., higher subharmonic-to-harmonic ratio). The interaction effect revealed a gender difference in the use of creakier voice to express sarcasm in Mandarin. The classification analysis using the random forest algorithm showed that the nine voice quality parameters resulted in 84.0% and 83.7% identification rates for sarcastic and sincere utterances, respectively. Conclusions The results of this preliminary study support the role of voice quality in expressing sarcasm in Mandarin speech. Using a set of voice quality parameters, sarcastic and sincere utterances can be effectively identified. Furthermore, there is a gender difference in the use of creakier voice in expressing Mandarin sarcastic speech. Supplemental Material https//doi.org/10.23641/asha.12743780.