ACL insufficiency can be caused by different reasons. Eganelisib Elevated posterior tibial slope is a deformity which is discussed to have relevant influence on the outcome of ACL surgery. A increased posterior tibial slope of 12° or more leads to significant more ACL insufficiency. The surgical therapy of this pathology is a high tibial extension osteotomy. Publications ashowing a clinical follow up and results of this surgery are rare. In this video the technique of a closed wedge high tibial extension osteotomy is shown. Osteosynthesis is performed with two screws and an anklestable plate osteosynthesis. An arthroscopy with bone graft filling of the femoral ACL tunnel is performed first, followed by filling of the tibial tunnel in an open approach.

 In primary care, abnormal liver chemistries are often being diagnosed unintentionally. In addition to paying attention to symptoms, it is crucial for an effective clarification which liver values are taken into account as indicators and when patients are referred for further diagnostics. It is also important to have a functioning collaboration between GPs and specialists. To date, there are hardly any current findings about the procedure and the challenges experienced by GPs in German-speaking countries when it comes to clarifying increased liver values.

 In the course of a survey based on several preliminary studies, a total of 2,701 GPs in Hesse and Baden-Württemberg were interviewed between October 2019 and March2020. The focus was on behavior and strategies with regard to the clarification of elevated liver values. In addition to the descriptive analysis, a factor analysis was performed.

 The results show various challenges and problems that primary care is confronted with in everyday practice. The liver function screening as part of the general medical check-up. The development of a GP-based guideline for dealing with increased liver values should be followed up.

 It seems sensible to take measures that contribute to greater professionalization and standardization of primary care diagnostics and to a more structured cooperation with gastroenterological specialists. These include, for example, a broader range of training and further education formats, the development of a validated diagnostic pathway for classifying and evaluating elevated liver enzymes (especially early detection of patients at increased risk for liver fibrosis or liver cirrhosis) or the establishment of a liver function screening as part of the general medical check-up. The development of a GP-based guideline for dealing with increased liver values should be followed up.

 The lack of suitable allografts limits the availability of liver transplantation in Germany. The quality of potentially available German donor livers has to date not been analyzed.

 Analysis of all donors for potential liver transplantations reported to the Eurotransplant by the German Organ Transplantation Foundation from 2010 to 2018. Categorization of transplanted and discarded organs utilizing available histopathological reports and predefined extended criteria for organ donation.

 A total of 8594 livers were offered for transplantation, of which 15.2 % were discarded. During the analysis period the proportion of donor livers from extended criteria donors increased from 65 % to 70 % (p = 0.005). In 2018, 21.3 % of offered donor livers were discarded, more than half (56.4 %) of these organs came from donors meeting multiple extended criteria. Livers were significantly more likely to be not transplanted, when from donors of older age (> 65 years; 41 vs. 28 %), BMI > 30 kg/m

(29vs. 14 %) or elevated transaminase levels (all p < 0,001).

 Despite the consistent organ scarcity in Germany, a relevant amount of livers cannot be transplanted due to a multitude of organ quality limitations. This should stimulate the search for concepts such as normothermic

machine perfusion to evaluate, protect and potentially improve organ quality.

 Despite the consistent organ scarcity in Germany, a relevant amount of livers cannot be transplanted due to a multitude of organ quality limitations. This should stimulate the search for concepts such as normothermic ex vivo machine perfusion to evaluate, protect and potentially improve organ quality.

From 2014 to 2018, an interdisciplinary consortium of scientists investigated the extent and possible causes of the sexual abuse of children in the area of responsibility of the Catholic Church in Germany. The study bears the acronym MHG (Mannheim / Heidelberg/Gießen) after the locations of the participating universities. The personnel file analysis identified 1670 Catholic clerics accused of sexual abuse of minors for the period from 1946 to 2014. For the Catholic Church specific conditions that favour the sexual abuse of minors could be identified.

A comparison of criminal records of accused clerics and perpetrators from other institutional contexts has been carried out.

Sexual offenses of priests are severe and the number of persons affected per convicted person is not less than that of perpetrators in other institutions; the duration of abuse by Catholic clerics is even significantly longer. Persons affected by sexual abuse in the context of the Catholic Church are significantly more often male. The Catholic Church has tried more extensively than other institutions to cover up accusations of sexual abuse of children or young people by clerics.

Prevention concepts must take greater account of the specific conditions of sexual abuse in the Catholic Church.

Prevention concepts must take greater account of the specific conditions of sexual abuse in the Catholic Church.Due to the increased lifetime prevalence and personal, social, and economic burden of mental disorders, psychiatry is in need of a significant change in several aspects of its clinical and research approaches. Over the last few decades, the development of personalized / precision medicine in psychiatry focusing on tailored therapies that fit each patient’s unique individual, physiological, and genetic profile has not achieved the same results as those obtained in other branches, such as oncology. The long-awaited revolution has not yet surfaced. There are various explanations for this including imprecise diagnostic criteria, incomplete understanding of the molecular pathology involved, absence of available clinical tools and, finally, the characteristics of the patient. Since then, the co-existence of the two terms has sparked a great deal of discussion around the definition and differentiation between the two types of psychiatry, as they often seem similar or even superimposable. Generally, the two terminologies are used indiscriminately, alternatively, and / or separately, within the same scientific works.