• Hoffmann Lauritzen posted an update 4 days, 9 hours ago

    Objective This study examined relationships between prosocial factors including altruism, compassion, social connectedness, spirituality, and volunteerism and measures of health in college students. Participants A total of N = 1,075 participants from four institutions across various regions of the U.S. were included. Methods Participants were sent email invitation via student listserv to participate in a survey of health and prosocial factors that was open for one month. Results Hierarchical linear regressions were completed to examine the influence of prosocial variables on perceptions of health and engagement in health behaviors. Social connectedness was a significant contributor to variance in all health measures, and the variables with the most variance explained were symptoms of depression (28.6%) and Health-Related Quality of Life (24.6%). Ceralasertib order Conclusions Institutions should prioritize programing to enhance social connectedness and other prosocial behaviors because of the positive effect these factors can have on health and health behaviors.Exposure to musculoskeletal disorders (MSDs) is prevalent risk among those working for the maintenance of machinery and equipment in industry. Participatory ergonomics (PE) at the workplace embodies a solid strategy for the implementation of MSDs prevention programs. This practical case describes a participatory ergonomics project implemented to improve MSDs prevention strategies for the safety of maintenance workers. Experienced workers and maintenance workers employed in an Italian company for the industrial processing of wool have been actively involved in the risk assessment, in the proposal of improvement interventions and in the proposal of new preventive strategies. Ergonomic training and guidance helped the workers to have a proactive role inside prevention process. PE can help in the preventive management of critical activities of maintenance, through the empowerment of workers, the identification of targeted and feasible solutions and by using ergonomics as a basis for improving health and safety at work.OBJECTIVE To determine the diagnostic efficacy and clinical value of preoperative computed tomography (CT) and magnetic resonance imaging (MRI) among patients with suspected temporal bone encephaloceles (TBE). STUDY DESIGN Retrospective chart review from 2006 to 2018. SETTING Tertiary referral center. SUBJECTS AND METHODS The subjects underwent surgery for a clinically suspected TBE or cerebrospinal fluid (CSF) leak. Preoperative imaging test characteristics of CT and MRI, including sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV), were calculated for TBE scans and compared with intraoperative findings. RESULTS Fifty-seven subjects with otorrhea, middle ear effusion, hearing loss, and/or meningitis with suspected TBE or CSF leak were identified. All had preoperative CT scans, and 61% (35/57) had preoperative MRI scans. Intraoperatively, 37 of 57 patients (65%) were found to have a TBE. CT scans (17% sensitivity, 100% specificity, 100% PPV, 46% NPV) were less sensitive than MRI (58% sensitivity, 100% specificity, 100% PPV, 24% NPV) for detecting TBEs. Furthermore, the time from initial scan to operative repair was significantly longer in those who had a CT followed by MRI scan compared with CT alone or a fused CT-MRI scan (mean = 68 vs 15 days, respectively; P = .004). CONCLUSION CT and MRI provide complementary information that may aid surgical planning. However, imaging cannot always rule out TBE. In cases with high clinical suspicion, surgical confirmation is often required for definitive diagnosis and treatment. The cost of an additional preoperative study should be considered before its use.Objective Describe the frequency and characteristics of unclaimed prescriptions from a pharmacy embedded within a student health services clinic. Methods Cross-sectional study of prescriptions received by an on-campus pharmacy between September 1-December 31, 2017 and September 1-December 31, 2018. Prescription data were extracted from the pharmacy administrative database and then categorized into medication classes and claimed versus unclaimed. Results The pharmacy received 18,337 prescriptions during the study periods. Medications classified as central nervous system (n = 5101, 27.8%), hormones (n = 3976; 21.7%), and anti-infective (n = 3262, 17.8%) medications were most common. A total of 2,609 prescriptions (14.2%) were left unclaimed by patients. The frequency of unclaimed prescriptions varied across medication classes, ranging from 9.0% (anti-infective) to 34.1% (genitourinary). Conclusions Approximately one in seven prescriptions went unclaimed at this on-campus pharmacy. Future research is needed to identify predictors for unclaimed prescriptions to develop effective interventions that improve medication adherence.Aim CYP2C19 genotyping is used to guide antiplatelet therapy after percutaneous coronary intervention (PCI). This study evaluated the potential impact of CYP2C19 and multigene pharmacogenomics (PGx) testing on medications beyond antiplatelet therapy in a real-world cohort of PCI patients that underwent CYP2C19 testing. Methodology & results Multiple medications with actionable PGx recommendations, including proton pump inhibitors, antidepressants and opioids, were commonly prescribed. Approximately 50% received a CYP2C19 metabolized medication beyond clopidogrel and 7% met criteria for a CYP2C19 genotype-guided intervention. A simulation analysis projected that 17.5 PGx-guided medication interventions per 100 PCI patients could have been made if multigene PGx results were available. Conclusion This suggests that CYP2C19 and multigene PGx results could be used to optimize medication prescribing beyond antiplatelet therapy in PCI patients.Objective To estimate the association between eating habits and quality of life (QOL) in Chilean university students. Participants 1,212 students from the Universidad de La Frontera, Chile (mean age 18.7 ± 2.15) were surveyed in January-March 2018. Methods Participants completed a cross-sectional self-report survey to evaluate QOL using the WHOQOL-BREF scale and eating habits with a food habits survey. Results Students reporting a better healthy eating habits score also presented a higher QOL. Eating breakfast and eating home-cooked meals is a protective factor for QOL in each domain. The consumption of sweet snacks was shown to be a risk factor for the physical health and environment domains. The consumption of fast food is shown as the greatest risk factor in the physical domain. Conclusion Healthy and unhealthy eating habits are associated with different dimensions of QOL. University authorities should develop new policies to improve the QOL of the entire university community.