Cooperation and competition are two basic modes of human interaction. Their underlying neural mechanisms, especially from an interpersonal perspective, have not been fully explored. Using the electroencephalograph-based hyperscanning technique, the present study investigated the neural correlates of both cooperation and competition within the same ecological paradigm using a classic motion-sensing tennis game. Both the inter-brain coupling (the inter-brain amplitude correlation and inter-brain phase-locking) and the intra-brain spectral power were analyzed. Only the inter-brain amplitude correlation showed a significant difference between cooperation and competition, with different spatial patterns at theta, alpha and beta frequency bands. Further inspection revealed distinct inter-brain coupling patterns for cooperation and competition; cooperation elicited positive inter-brain amplitude correlation at the delta and theta bands in extensive brain regions, while competition was associated with negative occipital inter-brain amplitude correlation at the alpha and beta bands. These findings add to our knowledge of the neural mechanisms of cooperation and competition and suggest the significance of adopting an inter-brain perspective in exploring the neural underpinnings of social interaction in ecological contexts.Glomerella leaf spot (GLS), a fungal disease caused by Colletotrichum fructicola (C. fructicola), severely affects apple quality and yield, yet few resistance genes have been identified in apple (Malus domestica Borkh.). check details Here we found a transcription factor MdWRKY17 significantly induced by C. fructicola infection in the susceptible apple cultivar ‘Gala’. MdWRKY17 overexpressing transgenic ‘Gala’ plants exhibited increased susceptibility to C. fructicola, whereas MdWRKY17 RNA-interference plants showed opposite phenotypes, indicating MdWRKY17 acts as a plant susceptibility factor during C. fructicola infection. Furthermore, MdWRKY17 directly bound to the promoter of the salicylic acid (SA) degradation gene Downy Mildew Resistant 6 (MdDMR6) and promoted its expression, resulting in reduced resistance to C. fructicola. Additionally, Mitogen-activated protein kinase 3 (MdMPK3)directly interacted with and phosphorylated MdWRKY17. Importantly, predicted phosphorylation residues in MdWRKY17 by MAPK kinase 4 (MdMEK4)-MdMPK3 were critical for the activity of MdWRKY17 to regulate MdDMR6 expression. In the six susceptible germplasms, MdWRKY17 levels were significantly higher than the six tolerant germplasms after infection, which corresponded with lower SA content, confirming the critical role of MdWRKY17-mediated SA degradation in GLS tolerance. Our study reveals a rapid regulatory mechanism of MdWRKY17, which is essential for SA degradation and GLS susceptibility, paving the way to generate GLS resistant apple.Preventive health behaviors such as hand hygiene are crucial amidst pandemics like COVID-19 but reports on nonadherence persist. This could be due to the lack of Consideration of Future Consequences (CFC), a cognitive-motivational construct known to improve health-related behaviors. Therefore, we examined the relationship between CFC and five behaviors-mask-wearing, social distancing, hand hygiene, excessive necessities buying, and COVID-19 information searching using an internet-based Singapore-wide survey conducted from April 20 to May 4, 2020. Behavioral differences 2 weeks before and after the state-wide confinement were examined using paired t-tests. Relationships between CFC and COVID-19 behaviors were examined using regression analyses adjusted for depression and anxiety. Participants were regrouped into three categories-increased behavior performance, maintained high performance, and maintained low performance where mean differences were analysed using MANOVA. Three hundred and thirty-six participants completed the survey (mean age, SD = 32.9 years [SD = 12.6]; 38.7% males). CFCfuture predicted mask wearing (B = 0.16; p less then .05), social distancing (B = 0.0.19; p less then .01), hand hygiene (B = 0.17; p less then .01), and information searching (B = 0.21; p less then .001). CFCimmediate predicted hand hygiene (B = 0.09; p less then .05), excessive necessities buying (B = 0.07; p less then .05) and information searching (B = 0.08; p less then .05). Anxiety predicted excessive buying (B = 0.08; p less then .05) and hand hygiene (B = 0.13; p less then .01). Post-hoc test showed significantly higher CFCfuture (p less then .01) in participants who increased and maintained high behavioral performance.Plants are plastic organisms that optimise growth in response to a changing environment. This adaptive capability is regulated by external cues, including light, which provides vital information about the habitat. Phytochrome photoreceptors detect far-red light, indicative of nearby vegetation, and elicit the adaptive shade-avoidance-syndrome (SAS), which is critical for plant survival. Plants exhibiting SAS are typically more elongated, with distinctive, small, narrow leaf blades. By applying SAS-inducing end-of-day far-red (EoD FR) treatments at different times during Arabidopsis (Arabidopsis thaliana) leaf 3 development, we have shown that SAS restricts leaf blade size through two distinct cellular strategies. Early SAS induction limits cell division, while later exposure limits cell expansion. This flexible strategy enables phytochromes to maintain control of leaf size through the proliferative and expansion phases of leaf growth. mRNAseq time course data, accessible through a community resource, coupled to a bioinformatics pipeline, identified pathways that underlie these dramatic changes in leaf growth. Phytochrome regulates a suite of major development pathways that control cell division, expansion, and cell fate. Further, phytochromes control cell proliferation through synchronous regulation of the cell cycle, DNA replication, DNA repair and cytokinesis, and play an important role in sustaining ribosome biogenesis and translation throughout leaf development.RNA-protein interactions play key roles in epigenetic, transcriptional and posttranscriptional regulation. To reveal the regulatory mechanisms of these interactions, global investigation of RNA-binding proteins (RBPs) and monitor their changes under various physiological conditions are needed. Herein, we developed a psoralen probe (PP)-based method for RNA tagging and ribonucleic-protein complex (RNP) enrichment. Isolation of both coding and noncoding RNAs and mapping of 2986 RBPs including 782 unknown candidate RBPs from HeLa cells was achieved by PP enrichment, RNA-sequencing and mass spectrometry analysis. The dynamics study of RNPs by PP enrichment after the inhibition of RNA synthesis provides the first large-scale distribution profile of RBPs bound to RNAs with different decay rates. Furthermore, the remarkably greater decreases in the abundance of the RBPs obtained by PP-enrichment than by global proteome profiling suggest that PP enrichment after transcription inhibition offers a valuable way for large-scale evaluation of the candidate RBPs.