In the absence of input from the external world, humans are still able to generate vivid mental images. This cognitive process, known as visual mental imagery, involves a network of prefrontal, parietal, inferotemporal, and occipital regions. Using multivariate pattern analysis (MVPA), previous studies were able to distinguish between the…[Read more]

The term synergism means that the overall therapeutic benefits should be greater than the sum of the effects of individual agents and that the optimal therapeutic efficacy can be achieved at reduced doses. Micellar systems usually fail to deliver multiple drugs to target sites at synergistic doses and thus are not able to maximize the antitumor…[Read more]

The percentage of adults subsequently achieving a hemoglobin A1C below 8% ranged from 83% (dulaglutide, sitagliptin) to 71% (canagliflozin). The rate of hypoglycemia was 25 per 1000 person-years for exenatide, 37 per 1000 person-years for dulaglutide, 28 per 1000 person-years for sitagliptin, 18 per 1000 person-years for canagliflozin, and 34 per…[Read more]

It is concluded that the spatial spread of the landfill gas in the gas distribution layer is predominantly affected by texture and compaction of the overlying methane oxidation layer. In terms of methane oxidation system design, the choice of material and construction method have more impact on gas permeability than seasonal changes in soil…[Read more]

PURPOSE A retrospective multi-center comparative study to evaluate whether pregnancy leads to the loss of deformity correction (LOC) in female patients surgically treated for idiopathic scoliosis. METHODS One hundred twenty-eight female patients underwent segmental spinal instrumentation and fusion for AIS between 1999 and 2014 were reviewed. Of…[Read more]

In contrast, lymphoma and PVL shared two resistance-associated (DRB3*0140101 and *00902) BoLA-DRB3 alleles. Interestingly, we found that PVL associated alleles, but not lymphoma associated alleles, are related with the anti-BLV gp51 antibody production level in cows. Overall, our study is the first to demonstrate that the BoLA-DRB3 polymorphism…[Read more]

Background and objective The volume of the intracerebral hemorrhage (ICH) obtained from CT scans is essential for quantification and treatment planning. However,a fast and accurate volume acquisition brings great challenges. On the one hand, it is both time consuming and operator dependent for manual segmentation, which is the gold standard for…[Read more]

Current conventional endoscopes have restricted the accuracy of treatment delivery and monitoring. Over the past decade, there have been major developments in nanotechnology and light triggered therapy, potentially allowing a better detection of challenging lesions and targeted treatment of malignancies in the gastrointestinal tract. Theranostics…[Read more]

4/P-signal transducer and activator of transcription 3 (STAT3) and extracellular signal-regulated kinase 1/2 (Erk) phosphorylation were also studied. RESULTS The number of CD19+ CD24hi CD38hi B cells in patients with AD was similar to that in healthy controls. However, B10 cells were decreased in patients with AD. The proportion of B10 cells was…[Read more]

ed with severity of pulmonary complications. © the authors; licensee ecancermedicalscience.Purpose/objectives Retrospective evidence suggests that the irradiation of stem cells in the periventricular zone (PVZ), specifically the subventricular zone (SVZ), to higher doses may be associated with improved outcomes. Materials/methods This was a…[Read more]

In conclusion, the murine model of infection may contribute to a better understanding of the zoonotic transmission of brucellosis.Triple-negative breast cancer (TNBC) is extremely aggressive and lacks effective therapy. SAM and SH3 domain containing1 (SASH1) has been implicated in TNBC as a candidate tumor suppressor; however, the mechanisms of…[Read more]