Finally, we review the main prophylactic strategies and current vaccine candidates against both hRSV and hMPV.Within this study, monolithic three-dimensional silica aerogel (SA) composite parts with super insulating properties are presented. A generic part based on fiber-reinforced (FR) silica aerogel for thermal insulation of the exhaust tubing…[Read more]

in English, German Zusammenfassung. Das femoroacetabuläre Impingement (FAI) beschreibt einen deformitätsbedingten, pathomechanischen Konflikt zwischen Femurkopf-Hals-Übergang und Acetabulum, der bei Bewegung auftritt und zu Schäden im Hüftgelenk führen kann. Mittlerweile ist nachgewiesen, dass insbesondere das Cam-FAI mit der Entstehung einer…[Read more]

Moreover, all bonds between boron and nitrogen in B9N9 molecule are single one. Study bonding characters for C6, C12, C16, and C20 molecules have confirmed that carbon-carbon bonds of cyclo[n]carbon changed gradually from double bonds to alternating single and triple bonds with increasing n value. The data from theory would give help for future…[Read more]

Glioblastoma (GBM) is the most common adult primary tumor of the CNS characterized by rapid growth and diffuse invasiveness into the brain parenchyma. The GBM resistance to chemotherapeutic drugs may be due to the presence of cancer stem cells (CSCs). The CSCs activate the same molecular pathways as healthy stem cells such as WNT, Sonic hedgehog…[Read more]

t findings provide contextually relevant evidence on ototoxicity assessment and management within this context. They raise important implications for guidelines adherence and translating knowledge, policies and guidelines into practice, clinical assessment and management protocols followed, appropriate resource allocation per programme, as well as…[Read more]

To investigate the etiopathogenesis of fatty liver hemorrhagic syndrome (FLHS) and the protective effects of resveratrol (RSV) against FLHS in laying hens, 144 healthy 90-day-old laying hens were randomly divided into 4 groups including control (Con) group, high-energy low-protein (HELP) group, RSV group, and HELP + RSV group, each of which…[Read more]

Ninety-four percent were male, 89.2% were ages 18-44 years. Seventy-nine percent had >1 year of grappling experience and 30% had >5 years. Of the 4307, 1443 (33.5%) reported being choked >500 times, 3257 (75.7%) have been choked to near-syncope, and 1198 (27.8%) have been choked unconscious. Two of the 4307 (0.05%) reported ongoing symptoms from…[Read more]

This implies that using solely census data for accessibility analysis could lead to certain errors, and adopting mobile-based population data would represent the real-world situations for solving problems of social inequity in primary medical care.Influenza B virus (IBV) belongs to the Orthomyxoviridae family and generally causes sporadic…[Read more]

Stilbenes is a class of natural polyphenols with 1,2-diphenylethylene as the skeleton structure which have structural and active diversity. However, there are fewer studies on their metabolic process, which limits the in-depth research and development of such components. An UPLC-MS/MS method simultaneously determining contents of ten stilbenes was…[Read more]

Single-cell RNA sequencing and direct comparison to fetal specimens suggest that the skin organoids are equivalent to the facial skin of human fetuses in the second trimester of development. Moreover, we show that skin organoids form planar hair-bearing skin when grafted onto nude mice. Together, our results demonstrate that nearly complete skin…[Read more]

Background Loss of function mutations in SGPL1 are associated with Sphingosine-1-phosphate lyase insufficiency syndrome, comprising steroid resistant nephrotic syndrome, and primary adrenal insufficiency (PAI) in the majority of cases. SGPL1 encodes sphingosine-1-phosphate lyase (SGPL1) which is a major modulator of sphingolipid signaling. Case…[Read more]