• Albright Drejer posted an update 3 days, 8 hours ago

    centration for solubilised CVM samples.The research deals with the effect of skylines on citizens’ pleasantness. The research method is based on the respondents’ judgment of the color images of the skylines. 360 citizens were asked to complete a questionnaire to express their opinions and preferences along with the reasons. Three types of nature, traditional, and contemporary skylines were identified as the dominant skylines. The results showed that people prefer the nature and the traditional skyline over the contemporary skyline. They introduced some features as peacefulness, memorability, and distinctiveness as the reasons for their choice. The people’s residence place could influence their attitudes toward the skyline, and most of those living in the areas with contemporary contexts selected the skyline of their contemporary context as the favorite skyline. They did not look for the sense of peacefulness in the skyline, but they underlined attractiveness. Variables of age and gender had no effect on the preferences; however, by an increase in education level, the tendency to select the traditional and contemporary skyline increased.[This corrects the article DOI 10.1016/j.heliyon.2021.e06661.].Chronic stress exposure is now accepted as a problem that can produce deleterious effects on both brain structure and function. Numerous studies have proposed the potential of fruit peels as vital sources for acetylcholinesterase (AChE) inhibitors and antioxidants. Clausena lansium (Lour.) or wampee (WP) fruit peel is a rich source of antioxidants and flavonoids that could prove beneficial for human health. Currently, there has been no scientific evidence supporting the potency of WP peel extract to combat or reverse the memory impairment induced by chronic restraint stress (CRS). Therefore, we aimed to investigate the AChE-inhibiting and neuroprotective effects of WP peel extracts against CRS-mediated oxidative stress and cognitive dysfunction in rats. Initial assessment of the extract revealed antioxidant capacity and high concentrations of polyphenols. Further, Wistar rats were dosed orally with the WP peel extract (200, 400, and 600 mg/kg daily) and kept in a restrainer for 4 h a day for 28 consecutive days. The object recognition and Morris water maze tests were used to determine cognitive functions. After sacrifice, biomarkers of oxidative stress and AChE inhibitory activity in brain homogenates of rats were also investigated. CRS exposure produced oxidative stress and increased AChE activity, changes that led to learning and memory impairment in the cognition tests. Improved memory, reduced AChE activity, and a decreased oxidative stress status were seen in rats treated with WP peel extract. Overall, supplementation with WP peel extract may exert cognitive-enhancing effects through antioxidative neuroprotection and inhibition of AChE activity against CRS-induced oxidative stress.Andrographis paniculata (Burm f.) Nees is a tropical plant native to Southeast Asia that has been used as an effective remedy for a wide variety of illnesses in traditional Chinese and Ayurvedic medicine. The antimicrobial activity of its crude extract had been shown to be due to its quorum quenching activity. The study determined the effect of purified extracted compounds from the leaf of A. paniculata, namely andrographolide, 14-deoxyandrographolide, 14-deoxy-12-hydroxyandrographolide and neoandrographolide on quorum sensing-mediated virulence mechanisms in clinical isolates of metallo-β-lactamase (MβL)-producing Pseudomonas aeruginosa. Their effect on the expression of the lasR gene, which codes for LasR, a transcription activator protein of the quorum sensing system in P. BafilomycinA1 aeruginosa was also determined using RT-qPCR. All the pure compounds significantly decreased the biofilm formation, protease production and swarming motility of the P. aeruginosa isolates compared to the untreated controls (p 0.05), suggesting equal potencies. Results show the potential of the isolated pure compounds from A. paniculata for use as antimicrobial agents as a result of their quorum quenching activities.While several educational institutions in India, in accordance to global practices, have adopted Web-Based Learning Management Systems (WLMS) to supplement classroom courses, it is largely seen that these WLMSs fail in their objectives, leading to little or no return on investments. The study aims to define the factors that affect students’ acceptance of a web-based learning management system and test the moderating effect of their academic involvement in the success of a WLMS. 477 valid questionnaires were collected from university/college students to empirically test the research model using the structural equation modelling approach. The results concludes that indirect and direct effects account for 49% of the variation in the intention to use, which is explained by technical system quality, information quality, educational quality, service quality of the technical support team and user satisfaction. High academic involvement moderates the impact of different service qualities of the WLMS on user satisfaction, intention to use the system, and success of the WLMS. Based on the findings, theoretical and managerial implications are discussed.Over the years, pipelines have been the most economic medium for transporting crude oil to production and distribution facilities in the Niger Delta area of Nigeria. However, damages to the pipelines in this area by interdiction have hampered the continuous flow of crude oil to the facilities. Consequently, the revenue of the government dwindles, and the environment is severely degraded. This study assesses the economic and environmental impacts of pipeline interdiction in the Niger Delta region. Data from National oil spills detection and response agency, Nigeria is used to map spatial distribution of oil spills using Kernel Density Estimation with Geographic Information System. Literature was assessed to synthesize the historical, socioeconomic, and environmental impacts of oil spills and pipeline interdiction. Soil samples were collected from study area to determine the types of hydrocarbon pollutants and their concentrations in comparison with uncontaminated sites in the area. Results show that the range of concentrations of total petroleum hydrocarbon (TPH) for the impacted soil (IMP) was 17.