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Boje Sargent posted an update 6 days, 5 hours ago
Objectives. This study aimed to examine moisture distribution and transfer in firefighter protective clothing when moisture from the atmosphere and skin sweat were considered simultaneously.Methods. A self-developed test apparatus was used to simulate moisture transfer through the protective clothing under exposure to thermal radiation. The weights of each layer of fabric before and after heat exposure were measured to analyze the moisture distribution and transfer. Results. The moisture level in each layer of fabric before the exposure presented an increase over the initial moisture content. After dry heat exposure, the moisture content in each layer of fabric reduced gradually. However, the existence of hot steam increased the moisture content stored in the fabric system and accelerated the moisture transmitting to the skin surface. In addition, the amount of outward water evaporation for dry heat exposure was moderately more than inward water evaporation, while the amount of inward water evaporation was greatly more than outward water evaporation for wet heat exposure. Conclusion. Moisture transfer in the firefighter protective clothing was a two-way transmission during both heat exposures. Understanding moisture transfer helps to provide proper guidance to improve the thermal protection of clothing and reduce steam burns.Sexual satisfaction plays an important role in relationship, mental, and even physical health. Activities that produce a state of flow create meaning in people’s lives. Although people who report high levels of sexual satisfaction describe their sex lives as being very meaningful, there is little research on the relationship between sexual satisfaction and flow. This study sought to address this gap. One hundred participants who were in monogamous relationships completed an online survey consisting of two questionnaires-the New Sexual Satisfaction Scale and the Core Dispositional Flow State Scale. We used partial least square structural equation modeling approach to examine the association between flow and sexual satisfaction. We found that flow was a statistically significant positive predictor of both partner-focused and personal sexual satisfaction. Our results indicate that there are no statistically significant gender differences.Fungi are being responsible for causing serious infections in humans and animals. The opportunistic microorganisms provoke environmental contaminations in health and storage facilities to represent a serious concern to health security. The present work investigates the antifungal activity of two amino-alcohols based cationic surfactants such as CnEtOH, CnPrOH (with n = 14 and 16 are the carbon numbers of alkyl chain and EtOH = Ethanol and PrOH = Propanol) against a collection of different Candida species (Candida tropicalis, Candida albicans, Candida auris, Cyberlindnera jadinii, Candida parapsilosis, Candida glabrata and Candida rugosa) respectively. The amino-alcohols based cationic surfactants exhibited good antifungal activity against all Candida strains tested with minimum inhibitory concentrations (MIC) ranging from 0.002 to 0.30 mM. The MIC evaluation shows an increase as a function of the hydrophobicity of all inhibitors against the majority of the Candida strains tested. The different location of the alcoholic OH function in the polar head shows the influence on the availability of N+ responsible for electrostatic interactions with the candidate’s cell walls, which remains a very important step in the mode of action of quaternary ammonium cationic surfactants. Hence, a 3D structure of lanosterol 14-α-demethylase enzyme from C. auris was constructed by homology modeling using an online SWISS-MODEL server. The predicted model was analyzed by serval servers. Furthermore, a molecular docking study was carried out to better understand the binding mechanism of lanosterol homologous protein with surfactant ligands. Then, the docked complexes lanosterol-surfactants were refined by the molecular dynamic simulation to analyze their interaction behavior during the simulation.Communicated by Ramaswamy H. Sarma.Soil salinity and the resulting salt stress it imposes on crop plants is a major problem for modern agriculture. Understanding how salt tolerance mechanisms in plants are regulated is therefore important. One regulatory mechanism is the APETALA2/Ethylene Responsive Factor (AP2/ERF) transcription factor family, including dehydration responsive element binding (DREB) transcription factors. By binding to DNA, specifically upstream of genes that play roles in salt tolerance pathways, DREB proteins upregulate expression of these genes. DREB in Triticum aestivum (wheat) cluster in sub-groups and in this study by scanning the recently extended predicted proteome of wheat for DREB, we increased the number of members of this sub-family. Using the wheat genome, we identified 576 genes coding for the AP2 domain of which 508 were identified to have one AP2 domain, a characteristic of the DREB/ERF subfamily. We confirmed the existing four sub-groups by sequence-based phylogenetic analyses but also identified 32 new DREB subfamily members, not belonging to any known sub-group. Transcription factor profile inference analysis identified two genes, TraesCS2B02G002700 and TraesCS2D02G015200, being homologous to DREB1A of Arabidopsis thaliana. Based on molecular simulation (25 ns) analysis, TraesCS2B02G002700 with a CCGAC motif was observed to interact very stably with DNA. In silico mutational analysis at the 19th position in the DREB domain of TraesCS2B02G002700-DNA complex indicated this as a stable part for recognizing and forming interaction with DNA. Moreover, six target genes were predicted having an upstream CCGAC motif regulated by TraesCS2B02G002700. Our study provides an overall framework for exploring the transcription factors in plants and identifying e.g. potential salt stress target genes.Communicated by Ramaswamy H. Metabolism inhibitor Sarma.The profession of policeman is one of the most stressful. It is associated with exposure to traumatic experiences. This research study aimed to determine the predictors of symptoms of post-traumatic stress disorder (PTSD) and occupational burnout and to examine how they correlated in policemen. We searched for these predictors in cognitive activity, and specifically in ruminations and perceived job stress. The study was conducted with 120 police officers who have experienced traumatic events related to their job. The study showed that intrusive ruminations serve as a predictor that intensifies PTSD, while certain stressful work conditions are predictors of burnout. The results suggest that numerous mechanisms are at play in the pathogenesis of PTSD and burnout. Police officers cope much better with exposure to traumatic stressors than with stressful work conditions. This leads to a practical conclusion regarding the necessity of preventing the everyday job stress experienced by police officers.